theHorse: What Medications are Safe for Mares

A new article on looks at the challenges you face if your pregnant mare needs medication – is it safe or not? How much is known about the effects of drugs on pregnant mares?

Pregnancy changes everything. Physiologic changes in the mare during pregnancy are enormous, but little published information about them exists.

“There is much we don’t know about drug safety in pregnant mares. Safety studies are usually done in geldings rather than pregnant mares, and we can’t always extrapolate. Mainly all we have is anecdotal use that suggests the majority of commonly used drugs are relatively safe for use in pregnant mares.”

—Margo Macpherson, DVM, MS, Dipl. ACT, professor of large animal reproduction at the University of Florida’s College of Veterinary Medicine, in Gainesville

The article includes a chart of drug categories and what we know, and continues with a rundown of each drug type with its risk factors.

Find out what we know and how to make decisions about drugs for your mare. Click here to read more on

Photo: 10marek.n, CC BY-SA 3.0 via Wikimedia Commons

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